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      劉加軍的個人首頁

      劉加軍醫(yī)生簡介

        教授、主任醫(yī)師

        醫(yī)學(xué)博士,博士后,血液病學(xué)專家,博士研究生導(dǎo)師。

        1. SCI 雜志 Anti-Cancer Drugs 編委( 2009 年 IF:2.23 )。

        2. 教育部“中國科技論文在線”特邀評審專家。

        3. British Journal of Hematology 、 International Journal of Cancer 、 Oncology 等多種雜志審稿人。

        4. 國家自然科學(xué)基金及廣東省自然科學(xué)基金評審專家。

        5. 歐洲腫瘤協(xié)會抗癌分會國際會員。

        6. 廣東省中西醫(yī)結(jié)合學(xué)會常委。

        7. 廣州市抗癌協(xié)會血液腫瘤分會常委。

        獲獎情況

        1.2004 年榮獲中山大學(xué)附屬三院優(yōu)秀中青年醫(yī)師獎,是中山大學(xué)“千百十人才工程”培養(yǎng)對象。

        2. 2006-2007 年以來被美國 Who\'s who in The Medicine and Healthcare (世界醫(yī)學(xué)與健康護(hù)理名人錄)收錄。

        3. 2006 年被評為教育部“新世紀(jì)優(yōu)秀人才”。

        4. 2008 及 2009 年教育部“科技論文在線”優(yōu)秀通訊評審專家。

        論  著:截至到目前為止,在國內(nèi)外核心期刊發(fā)表學(xué)術(shù)論文 50 余篇  ( 第一作者 ), 其中 SCI 收錄 20 余篇。

        以第一或通訊作者發(fā)表的主要代表論文(均為 SCI 收錄)有:

        1. Antibody directed lentiviral mediated double suicide gene therapy in MUC-1 positive leukemia in vitro and in vivo. Cell Transplant 2011(In Press)

        2. PPARγ Agonist Suppresses TLR4 Expression and TNF-α Production in LPS Stimulated Monocyte Leukemia Cells. Cell Biochem Biophys . 2010 Nov 23. [Epub ahead of print] ( 通訊作者 ) 。

        3. Inactivation of PI3k/Akt signaling pathway and activation of caspase-3 are involved in tanshinone I-induced apoptosis in myeloid leukemia cells in vitro. Annals of Hematology 2010; 89(5):1089–1097. (通訊作者)

        4. Down-Regulation of Telomerase Activity and Activation of Caspase Are Responsible for Tanshinone I-Induced Apoptosis in Monocyte Leukemia Cells. International Journal of Molecular Sciences 2010; 11(5): 2267-2280.

        5. Activation of peroxisome proliferator-activated receptor-gamma induces apoptosis on acute promyelocyti leukemia cells via downregulation of XIAP. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 2009; 24(5): 623-632.

        6. Peroxisome Proliferator-Activated Receptor γ (PPAR-γ) Agonist Rosiglitazone (RGZ) Inhibits HL-60 Cell Growth by Induction of Apoptosis. Lab Medicine 2009; 40(5):297-302.

        7. Tanshinone IIA inhibits leukemia THP-1 cell growth by induction of apoptosis. Oncology Reports 2009; 21(3): 1075-1081.

        8. Peroxisome Proliferator-Activated Receptor-g Agonist Rosiglitazone–Induced Apoptosis in Leukemia K562 Cells and Its Mechanisms of Action. International Journal of Toxicology 2009; 28(2):123-131.

        9. Ponicidin Inhibits Monocytic Leukemia Cell Growth by Induction of Apoptosis. International Journal of Molecular Sciences 2008 ; 9(11) : 2265-2277.

        10. Downregulation of cyclooxygenase-2 expression and activation of caspase-3 are involved in peroxisome proliferator-activated receptor-gamma agonists induced apoptosis in human monocyte leukemia cells in vitro. Annals of Hematology 2007;86 (3):173-183.

        11. Induction of apoptosis and inhibition of cell adhesive and invasive effects by tanshinone IIA in acute promyelocytic leukemia cells in vitro. Journal of Biomedical Science 2006; 13(12):813–823.

        12. Antiproliferation Effects of Oridonin on HPB-ALL Cells and Its Mechanisms of Action. American Journal of Hematology 2006; 81(2):86–94.

        13. Ponicidin, an Ent-Kaurane Diterpenoid Derived from a Constituent of the Herbal Supplement PC-SPES, Rabdosia rubescens , Induces Apoptosis by Activation of Caspase-3 and Mitochondrial Events in Lung Cancer Cells In Vitro. Cancer Investigation 2006; 24(2):136–148.

        14. Expression of survivin and bax/bcl -2 in peroxisome proliferator activated receptor-{gamma} ligands induces apoptosis on human myeloid leukemia cells in vitro . Annals of Oncology 2005; 16(3):455-459.

        15. Peroxisome proliferator activated receptor- ligands induced cell growth inhibition and its influence on matrix metalloproteinase activity in human myeloid leukemia cells. Cancer Chemotherapy and Pharmacology 2005;56(4):400-408.

        16. Oridonin-induced apoptosis in leukemia K562 cells and its mechanism. Neoplasma 2005;52 (3):225-230.

        17. Antiproliferation effects of ponicidin on human myeloid leukemia cells in vitro . Oncology Reports 2005; 13 (4):653-657.

        18. Apoptotic effect of oridonin on NB4 cells and its mechanism. Leukemia & Lymphoma 2005; 46 (4): 593-597.

        19. Antiproliferation effects of oridonin on HL-60 cells. Annals of Hematology 2004; 83(11):691-695.

        20. Anti-proliferative effects of oridonin on SPC-A-1 cells and its mechanism of action. Journal of International Medical Research 2004; 32 (6):617-625.

        21 . Oridonin Inhibit Cell Growth by Induction of Apoptosis on Human Carcinoma BEL7402 Cells.Hepatology Research . 2006;35(2)104-110.

        22 . Oridonin-induced apoptosis of Jurkat cells and its mechanism. Comparative Pathology.2004;13(2): 65-69.

        從事內(nèi)科血液學(xué)臨床醫(yī)療及科研工作近20年。多年以來從事白血病細(xì)胞凋亡

        信號轉(zhuǎn)導(dǎo)機(jī)制、血液腫瘤的分子靶向治療及抗白血病藥物的作用靶點等研究。 目

        前擔(dān)任歐洲國際著名SCI雜志 Anti-Cancer Drugs(2005年最新影響因子為:2.05)

        編委(Editorial borad), 國家自然科學(xué)基金委評審專家、 廣東省自然基金委評審

        專家?,F(xiàn)為美國血液學(xué)會會員,歐洲腫瘤協(xié)會抗癌分會國際會員,多年以來擔(dān)任

        British Journal of Hematology,International Journal of Cancer,Oncology

        等著名SCI雜志特約審稿人(Peer Reviewer)。曾經(jīng)參與完成國家自然科學(xué)基金

        2項,省自然科學(xué)基金4項。

        截至到目前為止,在國內(nèi)外核心期刊發(fā)表論文50余篇(第一作者), 其中SCI收

        錄14篇。 2006-2007年以來被美國 Who\'s who in The Medicine and Healthcare

        (世界醫(yī)學(xué)與健康護(hù)理名人錄)收錄。 2004年榮獲中山大學(xué)附屬三院優(yōu)秀中青年醫(yī)

        師獎。是中山大學(xué)“千百十人才工程”培養(yǎng)對象。 2006年科研課題榮獲教育部“新

        世紀(jì)優(yōu)秀人才支持計劃”資助。 多年來發(fā)表的一系列研究成果被國際醫(yī)學(xué)權(quán)威研究

        機(jī)構(gòu) complementary and Alternative Medicine Research 收錄。